UKE Microscopy Imaging Facility (DFG Research Infrastructure Portal: RI_00489)

Grunt M, Failla AV, Stevic I, Hillebrand T, Schwarzenbach H.
A novel assay for exosomal and cell-free miRNA isolation and quantification, RNA Biol. 2020, [PDF]
Yorgan TA, Sari H, Rolvien T, Windhorst S, Failla AV, Kornak U, Oheim R, Amling M, Schinke T.
Mice lacking plastin-3 display a specific defect of cortical bone acquisition. Bone. 2020 Jan;130:115062. [PDF]
Liu HY, Koch C, Haller A, Joosse SA, Kumar R, Vellekoop MJ, Horst LJ, Keller L, Babayan A, Failla AV, Jensen J, Peine S, Keplinger F, Fuchs H, Pantel K, Hirtz M.
Evaluation of Microfluidic Ceiling Designs for the Capture of Circulating Tumor Cells on a Microarray Platform. Adv. Biosys. 2019, 1900162 [PDF]
Sharaf A, Mensching L, Keller C, Rading S, Scheffold M, Palkowitsch L, Djogo N, Rezgaoui M, Kestler HA, Moepps B, Failla AV, Karsak M.
Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome. Front Mol Neurosci. 2019 Sep 20;12:224. eCollection 2019. [PDF]
Andres-Alonso M, Ammar MR, Butnaru I, Gomes GM, Acuña Sanhueza G, Raman R, Yuanxiang P, Borgmeyer M, Lopez-Rojas J, Raza SA, Brice N, Hausrat TJ, Macharadze T, Diaz-Gonzalez S, Carlton M, Failla AV, Stork O, Schweizer M, Gundelfinger ED, Kneussel M, Spilker C, Karpova A, Kreutz MR.
SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals. Nat Commun. 2019 Nov 29;10(1):5448. [PDF]
Herwig J, Skuza S, Sachs W, Sachs M,Failla AV, Rune G, Meyer TN, Fester L, Meyer-Schwesinger C.
Thrombospondin Type 1 Domain-Containing 7A Localizes to the Slit Diaphragm and Stabilizes Membrane Dynamics of Fully Differentiated Podocytes. J Am Soc Nephrol. 2019 May;30(5):824-839.
[Journal cover May 2019]
JASN cover May2019
Zobiak B, Failla AV
Visualizing adhesion formation in cells by means of advanced spinning disk-total internal reflection fluorescence microscopy. J Vis Exp. 2019 Jan 21, (143):e58756. [PDF]
Nauth T, Huschka F, Schweizer M, Bosse JB, Diepold A, Failla AV, Steffen A, Stradal T, Wolters M, Aepfelbacher M
Visualization of translocons in Yersinia type III protein secretion machines during host cell infection. PLoS Pathog. 2018 Dec 26;14(12):e1007527.
Diercks BP, Werner R, Weidemüller P, Czarniak F, Hernandez L, Lehmann C, Rosche A, Krüger A, Kaufmann U, Vaeth M, Failla AV, Zobiak B, Kandil FI, Schetelig D, Ruthenbeck A, Meier C, Lodygin D, Flügel A, Ren D, Wolf IM, Feske S, Guse AH
ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation. Sci. Signal 2018 Dec 18; 11(561) - [PDF]
Wang S, Brunne B, Zhao S, Chai X, Li J, Lau J, Failla AV, Zobiak B, Sibbe M, Westbrook GL, Lutz D, Frotscher M
Trajectory analysis unveils Reelin's role in the directed migration of granule cells in the dentate gyrus. J Neurosci. 2018 Jan 3; 38(1):137-148 - [PDF]
Zobiak B, Failla AV
Advanced spinning disk-TIRF microscopy for faster imaging of the cell interior and the plasma membrane. J Microsc. 2018 Mar;269(3):282-290 -[Article] [PDF]
Wackenhut F, Zobiak B, Meixner AJ, Failla AV
Tuning the fields focused by a high NA lens using spirally polarized beams. Chin Opt Lett. 2017; 15(3): 030013. [PDF]
Chai X, Zhao S, Fan L, Zhang W, Lu X, Shao H, Wang S, Song L, Failla AV, Zobiak B, Mannherz HG, Frotscher M
Reelin and cofilin cooperate during the migration of cortical neurons: A quantitative morphological analysis. Development. 2016 Mar 15;143(6):1029-40. [PDF]
Mathes C, Brandner JM, Laue M, Raesch SS, Hansen S, Failla AV, Vidal S, Moll I, Schaefer UF, Lehr CM
Tight junctions form a barrier in porcine hair follicles. Eur J Cell Biol. 2015 Dec 29. pii: S0171-9335(15)30022-4.
Wolters M, Zobiak B, Nauth T, Aepfelbacher M.
Analysis of Yersinia enterocolitica Effector Translocation into Host Cells Using Beta-lactamase Effector Fusions. J Vis Exp. 2015 Oct 13;(104). [PDF]
[UKE Paper of the Month July 2015]
Lin YN, Bhuwania R, Gromova K, Failla AV, Lange T, Riecken K, Linder S, Kneussel M, Izbicki JR, Windhorst S.
Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion. Oncotarget. 2015 May 25. [PDF]
Wackenhut F, Failla AV, Meixner AJ.
Single gold nanorods as optical probes for spectral imaging. Anal Bioanal Chem. 2015 May;407(14):4029-34. Epub 2015 Apr 9. [PDF]
Lin YN, Thata RN, Failla AV, Geissen M, Daum G, Windhorst S.
Ex vivo aorta patch model for analysis of cellular adhesion. Tissue Cell. 2015 Mar 23. pii:S0040-8166(15)00022-1.
Decker R, Burdelski C, Zobiak M, Büttner H, Franke G, Christner M, Saß K, Zobiak B, Henke HA, Horswill AR, Bischoff M, Bur S, Hartmann T, Schaeffer CR, Fey PD, Rohde H.
An 18 kDa Scaffold Protein Is Critical for Staphylococcus epidermidis Biofilm Formation. PLoS Pathog. 2015 Mar 23;11(3):e1004735. eCollection 2015 Mar. [PDF]
Ashour DJ, Pelka B, Jaaks P, Wundenberg T, Blechner C, Zobiak B, Failla AV, Windhorst S.
The catalytic domain of inositol-1,4,5-trisphosphate 3-kinase-a contributes to ITPKA-induced modulation of F-actin. Cytoskeleton (Hoboken). 2015 Jan 23. [PDF]
Kern AM, Zhang D, Brecht M, Chizhik AI, Failla AV, Wackenhut F, Meixner AJ.
Enhanced single-molecule spectroscopy in highly confined optical fields: from λ/2-Fabry-Pérot resonators to plasmonic nano-antennas. Chem Soc Rev. 2014 Feb 21;43(4):1263-86. [PDF]
Kollmann K, Pestka JM, Kühn SC, Schöne E, Schweizer M, Karkmann K, Otomo T, Catala-Lehnen P, Failla AV, Marshall RP, Krause M, Santer R, Amling M, Braulke T, Schinke T.
Decreased bone formation and increased osteoclastogenesis cause bone loss in mucolipidosis II. EMBO Mol Med. 2013 Dec;5(12):1871-86. [PDF]
Tilling T, Wladykowski E, Failla AV, Houdek P, Brandner JM, Moll I.
Immunohistochemical analyses point to epidermal origin of human Merkel cells. Histochem Cell Biol. 2014 Apr;141(4):407-21. [PDF]
Wackenhut F, Failla AV, and Meixner AJ
Multicolor Microscopy and Spectroscopy Reveals the Physics of the One-Photon Luminescence in Gold Nanorods. The Journal of Physical Chemistry C 2013 117 (34), 17870-17877. [PDF]
Wackenhut F, Failla AV, Meixner AJ.
Sensing dielectric media on the nanoscale with freely oriented gold nanorods. Phys Chem Chem Phys. 2013 Apr 21;15(15):5407-14. [PDF]
Wackenhut F, Failla AV, Züchner T, Steiner M, Meixner AJ
Three-dimensional photoluminescence mapping and emission anisotropy of single gold nanorods. Applied Physics Letters, 100, 263102 (2012), [PDF]
Jiao J, Wang X, Wackenhut F, Horneber A, Chen L, Failla AV, Meixner AJ, Zhang D.
Polarization-dependent SERS at differently oriented single gold nanorods. Chemphyschem. 2012 Mar;13(4):952-8. [PDF]
Kulemzina I, Schumacher MR, Verma V, Reiter J, Metzler J, Failla AV, Lanz C, Sreedharan VT, Rätsch G, Ivanov D.
Cohesin rings devoid of Scc3 and Pds5 maintain their stable association with the DNA. PLoS Genet. 2012;8(8):e1002856. [PDF]
Correa de Sampaio P, Auslaender D, Krubasik D, Failla AV, Skepper JN, Murphy G, English WR.
A heterogeneous in vitro three dimensional model of tumour-stroma interactions regulating sprouting angiogenesis. PLoS One. 2012;7(2):e30753. [PDF]
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